vbid/9780443161292

Description

Translational Models of Parkinson�s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson�s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson�s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.

• Highlights induction and validation of different available experimental models of Parkinson�s Disease
• Provides a comparative prospect of different experimental models of Parkinson�s Disease
• Discusses the advantages and disadvantages of each model, including associated limitations

Typham this is the title: Translational Models of Parkinson�s Disease and related Movement Disorders