vbid/9781461462200

Description

??The Hippo signaling pathway is�rapidly gaining recognition as an important player in organ size�control and tumorigenesis, and many leading scientists are showing�increased interest in this growing field and it’s relation to cancer.��The chapters in this volume�cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Ras, Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely involved in regulating �classic� tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. The primary audience are�researchers interested in basic science in the areas of�tumor suppression, cell cycle and size regulation, development and differentiation.Typham this is the title: The Hippo Signaling Pathway and Cancer