Description
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes�hypertension�and the majority with this disease�are undiagnosed for PA.�There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene � KCNJ5 � in about 40% of PA with adenoma. Chapters in this book�include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.Typham this is the title: Primary Aldosteronism Molecular Genetics, Endocrinology, and Translational Medicine
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