vbid/9783030887193

Description

The objective of this�third edition�is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist�s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound�s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at�a�minimum a working knowledge of each of the�above mentioned�facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.Typham this is the title: Formulating Poorly Water Soluble Drugs 3rd Edition