vbid/9783319306544

Description

This volume focuses on defining the unique attributes of using the�zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the�zebrafish model, the volume explores�oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most�prominent laboratories working in this field, which provides a unique perspective on�zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific�zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and�pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on�zebrafish and cancer, providing a much needed resource on the powerful attributes of the�zebrafish model system.Typham this is the title: Cancer and Zebrafish Mechanisms, Techniques, and Models